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According to the Simons Foundation Autism Research Initiative (SFARI) gene database ( as of November, 2020), there are up to now 284 genetic, 45 pharmacologically-induced, and 8 inbred mouse models of ASD

Abbreviations AI: Artificial intelligence CNC: Cellulose nanocrystals DFU: Diabetic foot ulcer EPS: Extracellular polymeric substances GOx: Glucose oxidase LCA: Life cycle assessment MMPs: Matrix metalloproteinases NC: Nanocellulose PLA: Polylactic acid ROS: Reactive oxygen species SCFA: Short-chain fatty acids TMAO: Trimethylamine N-oxide ECM: Extracellular matrix CFU: Colony-forming units References Collaborators GBDCoD

doi: 10.26355/eurrev_202102_24823 58

The researchers hypothesized that weight loss with AOD9604 was driven by the beta-adrenergic pathway, more specifically the beta(3)-adrenergic receptors